Dr. Edith M. Myers
Courses taught at FDU
Introduction to Neuroscience
Science Scholars Seminar
Current Topics in Biology
My lab is interested in understanding the molecular basis of behavior. Our approach is to use the model organism, C. elegans. C. elegans is a small roundworm with a simple, well-characterized nervous system, short generation time, and advanced genetics. These experimental advantages enable us to use genetics and molecular biology to study how important genes and signaling molecules control the development and function of neurons, and thus behavior. Because many of these genes and signaling molecules are similar between C. elegans and humans, what we learn about their roles in worms may help us understand their roles in the human nervous system. Currently, we are investigating how certain cell-signaling pathways regulate the expression of an important growth factor required for normal cell proliferation, differentiation, and neuronal synaptic plasticity in many animals (including humans). In the longer term, we would like to use C. elegans to understand the molecular mechanisms by which this growth factor regulates behavioral states and neuron morphology.
Postdoctoral training, Yale University School of Medicine
Ph.D., University of Pennsylvania, Neuroscience
B.A., University of Delaware, Biology
Myers, EM. (2014). Mapping a mutation in Caenorhabditis elegans using a polymerase chain reaction-based approach. Biochem. and Mol. Bio. Ed. 42(3):246-256.
Gardner, M*, Rosell, M*, and Myers, EM. (2013). Measuring the effects of bacteria on C. elegans behavior using an egg retention assay. J. Vis. Exp. (80), e51203, doi:10.3791/51203. *= FDU undergraduate students
Myers, EM. (2012). Gao and Gaq Regulate the Expression of daf-7, a TGFB-like Gene, in Caenorhabditis elegans. PLoS One 7(7):e40368.
Myers, EM. (2003). The Circadian Control of Eclosion. Invited review in Chronobiol. Intl.: The J. of Biol. and Med. Rhythm Res. 20(5):775-794.
Myers, EM, Yu, J, Sehgal, A. (2003). Circadian control of eclosion: Interaction between a central and peripheral clock in Drosophila melanogaster. Current Biology 13(6):526-533.
Tischkau, SA1, Barnes, JA1, Lin, F-J1, Myers, EM1, Soucy, JW, Meyer-Bernstein, E, Hurst, W, Burgoon, PW, Chen, D, Sehgal, A, and Gilette, M. (1999). Oscillation and light induction of timeless mRNA in the mammalian circadian clock. J. Neurosci. 19 (RC15). 1= these authors contributed equally to the work
Selected Conference Presentations
Sauer, C* and Myers, EM. (2014). Effects of Triclosan on Ryanodine Receptors in C. elegans. Poster at the William Paterson Undergraduate Research Symposium.
Thiagaram, D* and Myers, EM. (2014). Determining whether Escherichia coli OP50 pathogenesis in Caenorhabditis elegans is dependent upon insulin-like signaling. Poster at the William Paterson Undergraduate Research Symposium.
Gardner, M*, Graciano, T*, Middleton, JH and Myers, EM. (2013). Understanding the mechanism by which C. elegans alter their behavior in the presence of pathogenic bacteria. Poster at the American Society of Microbiology Meeting in Miniature, Rutgers University.
Rosell, M* and Myers, EM. (2013). Effects of the anti-microbial agent triclosan on C. elegans egg-laying behavior. Poster at the William Paterson Undergraduate Research Symposium (first place award in category).
Gardner, M*, Graciano, T*, Middleton, JH and Myers, EM. (2012) Characterizing C. elegans behavior in response to E. faecalis. Poster at the Aging, Metabolism, Stress, Pathogenesis, and small RNAs in C. elegans meeting, University of Wisconsin, Madison, WI.
Middleton, JH, Myers, EM, Gardner, MK*, Graciano, TR*, and Lettenberger, K*. (2012). Use of a Simplified C. elegans Assay to Detect Expressed Virulence Factors in Environmental Enterococcus faecalis Isolates. Poster at the 112th General Meeting, American Society for Microbiology. San Francisco, CA.
Myers, EM and Middleton, JH. (2011). Using C. elegans as a model to assay bacterial pathogenesis in an undergraduate research survey course. Poster at the 18th Annual International C. elegans meeting, University of Los Angeles, Los Angeles, CA.
Danzi, B*, Musanovic, M*, Shoenfeld, J* and Myers, EM. (2010). The role of G proteins in daf-7 expression and signaling. Poster at the Aging, Metabolism, Stress, Pathogenesis, and small RNAs in C. elegans meeting, University of Wisconsin, Madison, WI.
Danzi, B* and Myers, EM. (2010). Determining Components of the Dopamine Signaling Pathway in C. elegans. Poster at the Northeast Undergraduate Research Organization for Neuroscience meeting, Hunter College, New York, NY.
*= FDU undergraduate student
Phone: (973) 443-8766
Email: emyers @ fdu.edu
Office: East Cottage 1